Intergrative Mycology Lab​​



APRIL 2018​

1. Phani M. Gummadidala wins the DISCOVER USC 2018 POSTER AWARD second time in a row! Congratulations Phani!!

2. Dr. Ola Gomaa is 2018’s Egyptian Fulbright Scholar in Biotechnology! Her scholarship to work with the Chanda lab will allow her to study the Aspergillus niger biology linked with its bioremediation properties.

3. We have recently received a pilot project grant to investigate infectious diseases in spinal cord injury patients​.

4. Our paper on the long-term effects of antibiotics on colon cancer is accepted in cancer Medicine!    

Our funded projects

NIH Center of Dietary Supplements and Inflammation, Pilot project
Impacts of Δ9-tetrahydrocannabinol on gut microbiota and its metabolite profiles. The goal of this study is to elucidate how bacterial and fungal communities in the gut of C57BL/6 mice and their metabolites are impacted upon administration of Δ9-tetrahydrocannabinol.

USDA Project 6054-42000-021-26S (Agreement 58-6054-5-031)       
Molecular Factors involved in Aspergillus flavus development, secondary metabolism and survival.The goal of this collaborative study to elucidate the regulatory network underlying development and secondary metabolism in filamentous fungi.

USDA –NIFA                                                                           
TOXIMAP: Computational Framework for Prediction of Geographical and Temporal Incidence of Mycotoxins in US Crop Fields The goal of this study is to build a predictive software platform for US farmers, in which potential mycotoxin contamination in crops can be predicted using the geographical and environmental data.

Natural Resources Conservation Services/USDA               
Using Cover Crops and Soil Health to Reduce Crop Stress and Aflatoxin Contamination. The goal of the project is to develop in collaboration with SC farmers, natural means (use of cover crops) to reduce plant pathogen infestation of corn.

Watertech Inc. (Industrial Research Grant)                                     
A Proposed Study To Evaluate The Efficacy of Watertech’s Proprietary Disinfecting Solution In Selected Clinical Trials.
The goal of this project is to establish the anti-fungal properties of one proprietary industrial disinfecting solution.

NIH Center of Colon Cancer Research-Pilot project                      
Mechanical Landscaping of the Colon by Gut Microflora
The goal of this project was to understand how gut microbial community regulates the surface property of a gut epithelium. Two papers are in preparation provide evidence in APCmin/+ and C57BL/6 models that antibiotic mediated alteration of the gut microbiome changes the gut epithelium surface properties. The project already has used the methods proposed for this project.

ASPIRE II (USC Faculty Research Grant)                      
Uncertainty driven multiscale model development for aflatoxin prediction 
The goal of this project was to develop a mathematical model of a microbial colony’s growth and metabolite synthesis using environmental cues as input parameters. The project has used Aspergillus colony as a biological model.

SC Floods (USC Faculty Research Grant)                       
Investigation of mold infested USC buildings affected by October 2015 flood: comparison with original mold infested areas.The goal of this project is to collect data on the fungal communities that led to several indoor mold problems in USC buildings after the historical October 2015 floods in South Carolina.

ASPIRE I (USC Faculty Research Grant)
Purification and characterization of aflatoxin synthesis inhibitors from Penicillium Virginium  The goal of this study is to discover bioactive metabolites from an unknown fungal species, Penicillium virginium .

STUDENT AWARDS (2012-2017)

Best Poster Award: Phani M. Gummadidala (2017)
Doctoral Achievement Award: Chandrani Mitra (2016)
First Place in Discovery Day Poster Presentation: Nora Banaszek (2015)
Magellan Scholar: Nora Banaszek (2014)
Magellan Minigrant: Nora Banaszek (2014)
Acceptance to Ronald E. McNair Post-Baccalaureate Achievement Program: Sandra McFadden (2013)
Magellan Scholar: Sandra McFadden (2013)
Magellan Scholar: Sydney Bromfield (2013)
Magellan Guarantee: Sandra McFadden (2013)
American Society for Cell Biology MAC Travel Award: Sandra McFadden (2013)
National Hollings Fellow: Mallori Williams (2013)
Magellan Minigrant: Sandra McFadden (2012)